A club by the name of Plasmadoc FC was formed in 1874, and through a series of mergers between various local teams is claimed to be an ancestor of the modern Cefn Druids team who formed in 1992.

The team from the Plas Madoc Estate in Cefn Mawr, Wrexham County Borough, began playing again for the 2017–18 season in the North East Wales League, a competition which it won.

The following season, the team achieved second consecutive promotion when it won the Welsh National League Division One.

Unfortunately, on the 14th July 2020, an announcement via Twitter confirmed the club had folded citing issues raising funds as a result of the COVID-19 pandemic and the restructuring of the Welsh Football pyramid by the FAW.

Welsh National League - Division 1, Welsh National League - Premier Division
2019, 2020