| 2021-10-30 15:30:2030th October 2021 | Buckley Town | 15:30:203:30 pm | Guilsfield | JD Cymru North | 2022 | | - |
| 2021-10-23 14:30:4223rd October 2021 | Llandudno | 14:30:422:30 pm | Buckley Town | JD Cymru North | 2022 | | - |
| 2021-10-16 14:30:1116th October 2021 | Holyhead Hotspur | 14:30:112:30 pm | Llanrhaeadr | JD Cymru North | 2022 | | - |
| 2021-10-09 14:30:599th October 2021 | Penrhyncoch | 14:30:592:30 pm | Prestatyn Town | JD Cymru North | 2022 | | - |
| 2021-10-09 14:30:519th October 2021 | Llangefni Town | 14:30:512:30 pm | Llanidloes Town | JD Cymru North | 2022 | | - |
| 2021-10-09 14:30:239th October 2021 | Conwy Borough | 14:30:232:30 pm | Buckley Town | JD Cymru North | 2022 | | - |
| 2021-10-09 14:30:209th October 2021 | Airbus UK | 14:30:202:30 pm | Holywell Town | JD Cymru North | 2022 | | - |
| 2021-10-09 14:30:069th October 2021 | Holyhead Hotspur | 14:30:062:30 pm | Gresford Athletic | JD Cymru North | 2022 | | 7 |
| 2021-10-02 14:30:452nd October 2021 | Bangor City | 14:30:452:30 pm | Ruthin Town | JD Cymru North | 2022 | | - |
| 2021-10-02 14:30:432nd October 2021 | Colwyn Bay | 14:30:432:30 pm | Llandudno | JD Cymru North | 2022 | | - |
| 2021-10-02 14:30:332nd October 2021 | Llangefni Town | 14:30:332:30 pm | Prestatyn Town | JD Cymru North | 2022 | | - |
| 2021-10-02 14:30:272nd October 2021 | Buckley Town | 14:30:272:30 pm | Airbus UK | JD Cymru North | 2022 | | - |
| 2021-10-02 14:30:152nd October 2021 | Holyhead Hotspur | 14:30:152:30 pm | Penrhyncoch | JD Cymru North | 2022 | | - |
| 2021-10-02 14:30:122nd October 2021 | Llanrhaeadr | 14:30:122:30 pm | Conwy Borough | JD Cymru North | 2022 | | - |
| 2021-10-02 14:30:082nd October 2021 | Llanidloes Town | 14:30:082:30 pm | Guilsfield | JD Cymru North | 2022 | | - |
| 2021-10-01 19:30:431st October 2021 | Gresford Athletic | 19:30:437:30 pm | Holywell Town | JD Cymru North | 2022 | | - |
| 2021-09-28 19:30:0028th September 2021 | Ruthin Town | 19:30:007:30 pm | Prestatyn Town | JD Cymru North | 2022 | | 5 |
| 2021-09-18 14:30:5218th September 2021 | Guilsfield | 2 - 2 | Penrhyncoch | JD Cymru North | 2022 | | 10 |
| 2021-09-18 14:30:4718th September 2021 | Ruthin Town | 3 - 0 | Llanrhaeadr | JD Cymru North | 2022 | | 10 |
| 2021-09-18 14:30:4618th September 2021 | Llandudno | 3 - 0 | Llanidloes Town | JD Cymru North | 2022 | | 10 |
| 2021-09-18 14:30:3218th September 2021 | Conwy Borough | 0 - 0 | Holyhead Hotspur | JD Cymru North | 2022 | | 10 |
| 2021-09-18 14:30:1718th September 2021 | Prestatyn Town | 0 - 2 | Buckley Town | JD Cymru North | 2022 | | 10 |
| 2021-09-18 14:30:1618th September 2021 | Holywell Town | 3 - 3 | Bangor City | JD Cymru North | 2022 | | 10 |
| 2021-09-18 14:30:1318th September 2021 | Airbus UK | 4 - 1 | Colwyn Bay | JD Cymru North | 2022 | | 10 |
| 2021-09-17 19:30:0917th September 2021 | Gresford Athletic | 3 - 0 | Llangefni Town | JD Cymru North | 2022 | | 10 |
| 2021-09-11 14:30:4211th September 2021 | Bangor City | 0 - 2 | Gresford Athletic | JD Cymru North | 2022 | | 9 |
| 2021-09-11 14:30:4011th September 2021 | Penrhyncoch | 2 - 3 | Llandudno | JD Cymru North | 2022 | | 9 |
| 2021-09-11 14:30:3811th September 2021 | Llanrhaeadr | 0 - 4 | Holywell Town | JD Cymru North | 2022 | | 9 |
| 2021-09-11 14:30:2311th September 2021 | Holyhead Hotspur | 0 - 1 | Ruthin Town | JD Cymru North | 2022 | | 9 |
| 2021-09-11 14:30:0411th September 2021 | Llanidloes Town | 2 - 6 | Airbus UK | JD Cymru North | 2022 | | 9 |
| 2021-09-11 14:30:0411th September 2021 | Guilsfield | 2 - 1 | Conwy Borough | JD Cymru North | 2022 | | 9 |
| 2021-09-10 19:45:1210th September 2021 | Colwyn Bay | 3 - 2 | Prestatyn Town | JD Cymru North | 2022 | | 9 |
| 2021-09-10 19:45:0810th September 2021 | Llangefni Town | 2 - 3 | Buckley Town | JD Cymru North | 2022 | | 9 |
| 2021-09-07 19:45:197th September 2021 | Llandudno | 1 - 0 | Gresford Athletic | JD Cymru North | 2022 | | 5 |
| 2021-08-28 14:30:4528th August 2021 | Holywell Town | 1 - 2 | Holyhead Hotspur | JD Cymru North | 2022 | | 8 |
| 2021-08-28 14:30:2828th August 2021 | Airbus UK | 6 - 0 | Penrhyncoch | JD Cymru North | 2022 | | 8 |
| 2021-08-28 14:30:2228th August 2021 | Buckley Town | 1 - 0 | Colwyn Bay | JD Cymru North | 2022 | | 8 |
| 2021-08-28 14:30:0328th August 2021 | Prestatyn Town | 1 - 1 | Llanidloes Town | JD Cymru North | 2022 | | 8 |
| 2021-08-28 14:30:0328th August 2021 | Llandudno | 2 - 0 | Conwy Borough | JD Cymru North | 2022 | | 8 |
| 2021-08-27 19:30:5527th August 2021 | Bangor City | 6 - 0 | Llangefni Town | JD Cymru North | 2022 | | 8 |
| 2021-08-27 19:30:5527th August 2021 | Gresford Athletic | 4 - 0 | Llanrhaeadr | JD Cymru North | 2022 | | 8 |
| 2021-08-27 19:30:3527th August 2021 | Ruthin Town | 1 - 5 | Guilsfield | JD Cymru North | 2022 | | 8 |
| 2021-08-24 19:30:4124th August 2021 | Llanrhaeadr | 1 - 1 | Bangor City | JD Cymru North | 2022 | | 7 |
| 2021-08-24 19:30:3924th August 2021 | Llanidloes Town | 2 - 3 | Buckley Town | JD Cymru North | 2022 | | 7 |
| 2021-08-24 19:30:2924th August 2021 | Llangefni Town | 1 - 3 | Colwyn Bay | JD Cymru North | 2022 | | 7 |
| 2021-08-24 19:30:0424th August 2021 | Llandudno | 1 - 0 | Ruthin Town | JD Cymru North | 2022 | | 7 |
| 2021-08-24 19:30:0224th August 2021 | Guilsfield | 19:30:02Postponed | Holywell Town | JD Cymru North | 2022 | | 7 |
| 2021-08-24 19:30:0124th August 2021 | Conwy Borough | 1 - 4 | Airbus UK | JD Cymru North | 2022 | | 7 |
| 2021-08-21 14:30:4821st August 2021 | Colwyn Bay | 3 - 2 | Llanidloes Town | JD Cymru North | 2022 | | 6 |
| 2021-08-21 14:30:4021st August 2021 | Buckley Town | 2 - 3 | Penrhyncoch | JD Cymru North | 2022 | | 6 |
| 2021-08-21 14:30:3821st August 2021 | Prestatyn Town | 1 - 1 | Conwy Borough | JD Cymru North | 2022 | | 6 |
| 2021-08-21 14:30:3521st August 2021 | Holywell Town | 1 - 2 | Llandudno | JD Cymru North | 2022 | | 6 |
| 2021-08-21 14:30:3021st August 2021 | Llanrhaeadr | 0 - 0 | Llangefni Town | JD Cymru North | 2022 | | 6 |
| 2021-08-21 14:30:2921st August 2021 | Airbus UK | 2 - 1 | Ruthin Town | JD Cymru North | 2022 | | 6 |
| 2021-08-20 19:30:4220th August 2021 | Gresford Athletic | 0 - 2 | Guilsfield | JD Cymru North | 2022 | | 6 |
| 2021-08-20 19:30:0120th August 2021 | Bangor City | 3 - 1 | Holyhead Hotspur | JD Cymru North | 2022 | | 6 |
| 2021-08-14 14:30:5614th August 2021 | Penrhyncoch | 0 - 4 | Colwyn Bay | JD Cymru North | 2022 | | 5 |
| 2021-08-14 14:30:2514th August 2021 | Guilsfield | 4 - 2 | Bangor City | JD Cymru North | 2022 | | 5 |
| 2021-08-14 14:30:2414th August 2021 | Conwy Borough | 3 - 2 | Llanrhaeadr | JD Cymru North | 2022 | | 5 |
| 2021-08-10 19:45:1410th August 2021 | Colwyn Bay | 1 - 2 | Conwy Borough | JD Cymru North | 2022 | | 4 |
| 2021-08-10 19:30:5310th August 2021 | Bangor City | 3 - 3 | Llandudno | JD Cymru North | 2022 | | 4 |
| 2021-08-10 19:30:3710th August 2021 | Holyhead Hotspur | 2 - 0 | Llangefni Town | JD Cymru North | 2022 | | 4 |
| 2021-08-10 19:30:3310th August 2021 | Llanrhaeadr | 0 - 2 | Guilsfield | JD Cymru North | 2022 | | 4 |
| 2021-08-10 19:30:2910th August 2021 | Gresford Athletic | 0 - 1 | Airbus UK | JD Cymru North | 2022 | | 4 |
| 2021-08-10 19:30:2310th August 2021 | Llanidloes Town | 2 - 2 | Penrhyncoch | JD Cymru North | 2022 | | 4 |
| 2021-08-10 19:30:1910th August 2021 | Buckley Town | 5 - 0 | Ruthin Town | JD Cymru North | 2022 | | 4 |
| 2021-08-10 19:30:0710th August 2021 | Prestatyn Town | 2 - 1 | Holywell Town | JD Cymru North | 2022 | | 4 |
| 2021-07-31 14:30:5831st July 2021 | Airbus UK | 1 - 4 | Bangor City | JD Cymru North | 2022 | | 3 |
| 2021-07-31 14:30:4431st July 2021 | Holywell Town | 2 - 3 | Buckley Town | JD Cymru North | 2022 | | 3 |
| 2021-07-31 14:30:4131st July 2021 | Conwy Borough | 1 - 3 | Llanidloes Town | JD Cymru North | 2022 | | 3 |
| 2021-07-31 14:30:3731st July 2021 | Guilsfield | 3 - 0 | Holyhead Hotspur | JD Cymru North | 2022 | | 3 |
| 2021-07-31 14:30:3031st July 2021 | Llangefni Town | 1 - 5 | Penrhyncoch | JD Cymru North | 2022 | | 3 |
| 2021-07-31 14:30:1231st July 2021 | Colwyn Bay | 0 - 1 | Ruthin Town | JD Cymru North | 2022 | | 3 |
| 2021-07-31 14:30:0331st July 2021 | Prestatyn Town | 1 - 2 | Gresford Athletic | JD Cymru North | 2022 | | 3 |
| 2021-07-31 14:30:0131st July 2021 | Llanrhaeadr | 1 - 3 | Llandudno | JD Cymru North | 2022 | | 3 |
| 2021-07-27 19:45:2627th July 2021 | Airbus UK | 5 - 0 | Llangefni Town | JD Cymru North | 2022 | | 2 |
| 2021-07-27 19:30:5827th July 2021 | Llanidloes Town | 0 - 0 | Llanrhaeadr | JD Cymru North | 2022 | | 2 |
| 2021-07-27 19:30:4727th July 2021 | Guilsfield | 1 - 1 | Buckley Town | JD Cymru North | 2022 | | 2 |
| 2021-07-27 19:30:3927th July 2021 | Holywell Town | 1 - 1 | Ruthin Town | JD Cymru North | 2022 | | 2 |
| 2021-07-27 19:30:3527th July 2021 | Conwy Borough | 0 - 0 | Gresford Athletic | JD Cymru North | 2022 | | 2 |
| 2021-07-27 19:30:3327th July 2021 | Prestatyn Town | 1 - 1 | Llandudno | JD Cymru North | 2022 | | 2 |
| 2021-07-27 19:30:2627th July 2021 | Holyhead Hotspur | 0 - 0 | Colwyn Bay | JD Cymru North | 2022 | | 2 |
| 2021-07-27 19:30:0227th July 2021 | Penrhyncoch | 0 - 1 | Bangor City | JD Cymru North | 2022 | | 2 |
| 2021-07-24 14:30:5324th July 2021 | Holywell Town | 2 - 2 | Llanidloes Town | JD Cymru North | 2022 | | 1 |
| 2021-07-24 14:30:4424th July 2021 | Conwy Borough | 1 - 0 | Llangefni Town | JD Cymru North | 2022 | | 1 |
| 2021-07-24 14:30:4424th July 2021 | Airbus UK | 1 - 0 | Holyhead Hotspur | JD Cymru North | 2022 | | 1 |
| 2021-07-24 14:30:2824th July 2021 | Penrhyncoch | 1 - 1 | Ruthin Town | JD Cymru North | 2022 | | 1 |
| 2021-07-24 14:30:0624th July 2021 | Guilsfield | 3 - 0 | Llandudno | JD Cymru North | 2022 | | 1 |
| 2021-07-24 14:30:0324th July 2021 | Prestatyn Town | 3 - 1 | Llanrhaeadr | JD Cymru North | 2022 | | 1 |
| 2021-07-23 19:30:2923rd July 2021 | Gresford Athletic | 0 - 3 | Colwyn Bay | JD Cymru North | 2022 | | 1 |
| 2021-07-23 19:30:2623rd July 2021 | Buckley Town | 1 - 0 | Bangor City | JD Cymru North | 2022 | | 1 |
